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A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb+/− rats
Tumors caused by loss-of-function mutations in genes encoding TCA cycle enzymes have been recently discovered and are now of great interest. Mutations in succinate dehydrogenase (SDH) subunits cause pheochromocytoma/paraganglioma (PCPG) and syndromically associated tumors, which differ phenotypicall...
Autores principales: | Powers, James F, Cochran, Brent, Baleja, James D, Sikes, Hadley D, Pattison, Andrew D, Zhang, Xue, Lomakin, Inna, Shepard-Barry, Annette, Pacak, Karel, Moon, Sun Jin, Langford, Troy F, Stein, Kassi Taylor, Tothill, Richard W, Ouyang, Yingbin, Tischler, Arthur S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219221/ https://www.ncbi.nlm.nih.gov/pubmed/32252027 http://dx.doi.org/10.1530/ERC-19-0474 |
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