A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb+/− rats

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Tumors caused by loss-of-function mutations in genes encoding TCA cycle enzymes have been recently discovered and are now of great interest. Mutations in succinate dehydrogenase (SDH) subunits cause pheochromocytoma/paraganglioma (PCPG) and syndromically associated tumors, which differ phenotypicall...

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Detalles Bibliográficos
Autores principales: Powers, James F, Cochran, Brent, Baleja, James D, Sikes, Hadley D, Pattison, Andrew D, Zhang, Xue, Lomakin, Inna, Shepard-Barry, Annette, Pacak, Karel, Moon, Sun Jin, Langford, Troy F, Stein, Kassi Taylor, Tothill, Richard W, Ouyang, Yingbin, Tischler, Arthur S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219221/
https://www.ncbi.nlm.nih.gov/pubmed/32252027
http://dx.doi.org/10.1530/ERC-19-0474
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