Rational Vaccine Design in the Time of COVID-19

As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term “rational vaccine design.” We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses including HIV and...

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Detalles Bibliográficos
Autores principales: Burton, Dennis R., Walker, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219357/
https://www.ncbi.nlm.nih.gov/pubmed/32407707
http://dx.doi.org/10.1016/j.chom.2020.04.022
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author Burton, Dennis R.
Walker, Laura M.
author_facet Burton, Dennis R.
Walker, Laura M.
author_sort Burton, Dennis R.
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description As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term “rational vaccine design.” We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses including HIV and influenza, as well as coronaviruses.
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spelling pubmed-72193572020-05-13 Rational Vaccine Design in the Time of COVID-19 Burton, Dennis R. Walker, Laura M. Cell Host Microbe Forum As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term “rational vaccine design.” We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses including HIV and influenza, as well as coronaviruses. Elsevier Inc. 2020-05-13 2020-05-13 /pmc/articles/PMC7219357/ /pubmed/32407707 http://dx.doi.org/10.1016/j.chom.2020.04.022 Text en © 2020 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Forum
Burton, Dennis R.
Walker, Laura M.
Rational Vaccine Design in the Time of COVID-19
title Rational Vaccine Design in the Time of COVID-19
title_full Rational Vaccine Design in the Time of COVID-19
title_fullStr Rational Vaccine Design in the Time of COVID-19
title_full_unstemmed Rational Vaccine Design in the Time of COVID-19
title_short Rational Vaccine Design in the Time of COVID-19
title_sort rational vaccine design in the time of covid-19
topic Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219357/
https://www.ncbi.nlm.nih.gov/pubmed/32407707
http://dx.doi.org/10.1016/j.chom.2020.04.022
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