D-dimer in patients infected with COVID-19 and suspected pulmonary embolism

OBJECTIVE: To analyze the risk factors for pulmonary embolism (PE) in patients infected with COVID-19. METHODS: We conducted an observational, retrospective study. Patients with severe infection with COVID-19 and suspected PE were included. RESULTS: Patients with higher levels of D-dimer and those r...

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Autores principales: Garcia-Olivé, Ignasi, Sintes, Helena, Radua, Joaquim, Abad Capa, Jorge, Rosell, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219417/
https://www.ncbi.nlm.nih.gov/pubmed/32454268
http://dx.doi.org/10.1016/j.rmed.2020.106023
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author Garcia-Olivé, Ignasi
Sintes, Helena
Radua, Joaquim
Abad Capa, Jorge
Rosell, Antoni
author_facet Garcia-Olivé, Ignasi
Sintes, Helena
Radua, Joaquim
Abad Capa, Jorge
Rosell, Antoni
author_sort Garcia-Olivé, Ignasi
collection PubMed
description OBJECTIVE: To analyze the risk factors for pulmonary embolism (PE) in patients infected with COVID-19. METHODS: We conducted an observational, retrospective study. Patients with severe infection with COVID-19 and suspected PE were included. RESULTS: Patients with higher levels of D-dimer and those requiring intubation were at a higher risk of developing PE. Higher D-dimer levels were associated with a greater probability of PE 3, 6, 9 and 12 days after determining D-dimer levels with an OR of 1.7, 2.0, 2.4 and 2.4, respectively. CONCLUSION: In conclusion, patients infected with COVID-19 requiring OTI with higher levels of D-dimer have an increased risk of developing PE.
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spelling pubmed-72194172020-05-13 D-dimer in patients infected with COVID-19 and suspected pulmonary embolism Garcia-Olivé, Ignasi Sintes, Helena Radua, Joaquim Abad Capa, Jorge Rosell, Antoni Respir Med Article OBJECTIVE: To analyze the risk factors for pulmonary embolism (PE) in patients infected with COVID-19. METHODS: We conducted an observational, retrospective study. Patients with severe infection with COVID-19 and suspected PE were included. RESULTS: Patients with higher levels of D-dimer and those requiring intubation were at a higher risk of developing PE. Higher D-dimer levels were associated with a greater probability of PE 3, 6, 9 and 12 days after determining D-dimer levels with an OR of 1.7, 2.0, 2.4 and 2.4, respectively. CONCLUSION: In conclusion, patients infected with COVID-19 requiring OTI with higher levels of D-dimer have an increased risk of developing PE. Elsevier Ltd. 2020-08 2020-05-13 /pmc/articles/PMC7219417/ /pubmed/32454268 http://dx.doi.org/10.1016/j.rmed.2020.106023 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Garcia-Olivé, Ignasi
Sintes, Helena
Radua, Joaquim
Abad Capa, Jorge
Rosell, Antoni
D-dimer in patients infected with COVID-19 and suspected pulmonary embolism
title D-dimer in patients infected with COVID-19 and suspected pulmonary embolism
title_full D-dimer in patients infected with COVID-19 and suspected pulmonary embolism
title_fullStr D-dimer in patients infected with COVID-19 and suspected pulmonary embolism
title_full_unstemmed D-dimer in patients infected with COVID-19 and suspected pulmonary embolism
title_short D-dimer in patients infected with COVID-19 and suspected pulmonary embolism
title_sort d-dimer in patients infected with covid-19 and suspected pulmonary embolism
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219417/
https://www.ncbi.nlm.nih.gov/pubmed/32454268
http://dx.doi.org/10.1016/j.rmed.2020.106023
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