A Case Report of Angioedema and Anaphylactic Shock Induced by Ingestion of Polyethylene Glycol

INTRODUCTION: We report one of few documented cases of a severe anaphylactic reaction with angioedema to polyethylene glycol (PEG). CASE REPORT: The patient presented 30 minutes after onset of his symptoms and quickly developed hypoxia and hypotension refractory to intramuscular epinephrine, intrave...

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Detalles Bibliográficos
Autores principales: Rossi, Amy, Osborn, Lesley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219999/
https://www.ncbi.nlm.nih.gov/pubmed/32426669
http://dx.doi.org/10.5811/cpcem.2020.3.45218
Descripción
Sumario:INTRODUCTION: We report one of few documented cases of a severe anaphylactic reaction with angioedema to polyethylene glycol (PEG). CASE REPORT: The patient presented 30 minutes after onset of his symptoms and quickly developed hypoxia and hypotension refractory to intramuscular epinephrine, intravenous fluids, methylprednisolone, and supplemental oxygen via non-rebreather mask. He ultimately required intubation, an epinephrine infusion, and admission to the medical intensive care unit. DISCUSSION: This case depicts a clinical reaction to PEG, a medication rarely implicated in severe anaphylaxis or angioedema. CONCLUSION: The allergenic potential of PEG-containing products should be raised, and providers should have a heightened awareness of these potential side effects.

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