Cargando…
Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study
Acute postsurgical pain, probably including acute neuropathic pain (ANeP), starts at the early postoperative period, and chronic postsurgical pain including chronic neuropathic pain (CNeP) persists at least 3 months after surgery. Although it must be important for prevention and treatment of acute a...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220428/ https://www.ncbi.nlm.nih.gov/pubmed/32221089 http://dx.doi.org/10.1097/MD.0000000000019629 |
_version_ | 1783533159542947840 |
---|---|
author | Takenaka, Shiho Saeki, Ayano Sukenaga, Norihiko Ueki, Ryusuke Kariya, Nobutaka Tatara, Tsuneo Hirose, Munetaka |
author_facet | Takenaka, Shiho Saeki, Ayano Sukenaga, Norihiko Ueki, Ryusuke Kariya, Nobutaka Tatara, Tsuneo Hirose, Munetaka |
author_sort | Takenaka, Shiho |
collection | PubMed |
description | Acute postsurgical pain, probably including acute neuropathic pain (ANeP), starts at the early postoperative period, and chronic postsurgical pain including chronic neuropathic pain (CNeP) persists at least 3 months after surgery. Although it must be important for prevention and treatment of acute and chronic postoperative pain to reveal the time course of postoperative neuropathic characteristics, a neuropathic pain profile after surgery has not been evaluated. Pain status at the surgical site in adult patients who underwent video-assisted thoracic surgery (VATS) for lung cancer was prospectively assessed until 12 months after surgery. Neuropathic characteristics were assessed using the Douleur Neuropathique 4 (DN4) questionnaire until 6 days after surgery and the DN2 questionnaire throughout the study. Twenty-seven patients were enrolled in this study. Pain intensity at surgical sites were significantly higher at 1 and 6 days after surgery during resting state, and were also significantly higher at 3, 6, and 12 months after surgery during movement than those before surgery. The incidence of ANeP was 33.3% at 1 day, and 18.5% at 6 days after surgery. The incidence of CNeP decreased to 12.5% at 3 months, 5.0% at 6 months, and 0.0% at 12 months after surgery. The number of neuropathic characteristics, assessed by DN2 scores, significantly increased at 1 and 6 days after surgery, compared to those before surgery. DN2 scores at 3, 6, and 12 months after surgery, however, showed no significant differences compared to those before surgery. In patients with acute postsurgical pain, 20% to 30% of patients show ANeP characteristics, and the incidence of CNeP gradually decreases after VATS in patients with chronic postsurgical pain. |
format | Online Article Text |
id | pubmed-7220428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-72204282020-06-15 Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study Takenaka, Shiho Saeki, Ayano Sukenaga, Norihiko Ueki, Ryusuke Kariya, Nobutaka Tatara, Tsuneo Hirose, Munetaka Medicine (Baltimore) 3300 Acute postsurgical pain, probably including acute neuropathic pain (ANeP), starts at the early postoperative period, and chronic postsurgical pain including chronic neuropathic pain (CNeP) persists at least 3 months after surgery. Although it must be important for prevention and treatment of acute and chronic postoperative pain to reveal the time course of postoperative neuropathic characteristics, a neuropathic pain profile after surgery has not been evaluated. Pain status at the surgical site in adult patients who underwent video-assisted thoracic surgery (VATS) for lung cancer was prospectively assessed until 12 months after surgery. Neuropathic characteristics were assessed using the Douleur Neuropathique 4 (DN4) questionnaire until 6 days after surgery and the DN2 questionnaire throughout the study. Twenty-seven patients were enrolled in this study. Pain intensity at surgical sites were significantly higher at 1 and 6 days after surgery during resting state, and were also significantly higher at 3, 6, and 12 months after surgery during movement than those before surgery. The incidence of ANeP was 33.3% at 1 day, and 18.5% at 6 days after surgery. The incidence of CNeP decreased to 12.5% at 3 months, 5.0% at 6 months, and 0.0% at 12 months after surgery. The number of neuropathic characteristics, assessed by DN2 scores, significantly increased at 1 and 6 days after surgery, compared to those before surgery. DN2 scores at 3, 6, and 12 months after surgery, however, showed no significant differences compared to those before surgery. In patients with acute postsurgical pain, 20% to 30% of patients show ANeP characteristics, and the incidence of CNeP gradually decreases after VATS in patients with chronic postsurgical pain. Wolters Kluwer Health 2020-03-27 /pmc/articles/PMC7220428/ /pubmed/32221089 http://dx.doi.org/10.1097/MD.0000000000019629 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 3300 Takenaka, Shiho Saeki, Ayano Sukenaga, Norihiko Ueki, Ryusuke Kariya, Nobutaka Tatara, Tsuneo Hirose, Munetaka Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study |
title | Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study |
title_full | Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study |
title_fullStr | Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study |
title_full_unstemmed | Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study |
title_short | Acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: A prospective study |
title_sort | acute and chronic neuropathic pain profiles after video-assisted thoracic surgery: a prospective study |
topic | 3300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220428/ https://www.ncbi.nlm.nih.gov/pubmed/32221089 http://dx.doi.org/10.1097/MD.0000000000019629 |
work_keys_str_mv | AT takenakashiho acuteandchronicneuropathicpainprofilesaftervideoassistedthoracicsurgeryaprospectivestudy AT saekiayano acuteandchronicneuropathicpainprofilesaftervideoassistedthoracicsurgeryaprospectivestudy AT sukenaganorihiko acuteandchronicneuropathicpainprofilesaftervideoassistedthoracicsurgeryaprospectivestudy AT uekiryusuke acuteandchronicneuropathicpainprofilesaftervideoassistedthoracicsurgeryaprospectivestudy AT kariyanobutaka acuteandchronicneuropathicpainprofilesaftervideoassistedthoracicsurgeryaprospectivestudy AT tataratsuneo acuteandchronicneuropathicpainprofilesaftervideoassistedthoracicsurgeryaprospectivestudy AT hirosemunetaka acuteandchronicneuropathicpainprofilesaftervideoassistedthoracicsurgeryaprospectivestudy |