Cargando…
Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report
RATIONALE: The malignant potential and the appropriate treatment of uterine tumor resembling ovarian sex-cord tumor (UTROSCT) is controversial. Although these tumors generally have benign outcomes, several reports have described recurrences, metastases, and deaths associated with this disease. PATIE...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220453/ https://www.ncbi.nlm.nih.gov/pubmed/32176042 http://dx.doi.org/10.1097/MD.0000000000019166 |
_version_ | 1783533165460062208 |
---|---|
author | Sato, Miho Yano, Mitsutake Sato, Shimpei Aoyagi, Yoko Aso, Saki Matsumoto, Harunobu Yamamoto, Ichiro Nasu, Kaei |
author_facet | Sato, Miho Yano, Mitsutake Sato, Shimpei Aoyagi, Yoko Aso, Saki Matsumoto, Harunobu Yamamoto, Ichiro Nasu, Kaei |
author_sort | Sato, Miho |
collection | PubMed |
description | RATIONALE: The malignant potential and the appropriate treatment of uterine tumor resembling ovarian sex-cord tumor (UTROSCT) is controversial. Although these tumors generally have benign outcomes, several reports have described recurrences, metastases, and deaths associated with this disease. PATIENT CONCERNS: A 57-year-old Japanese woman (gravida 2, para 2) was referred to our hospital for the evaluation and treatment of uterine fibroids. Magnetic resonance imaging revealed a right ovarian mass and multiple fibroids in the uterine myometrium. DIAGNOSES: The patient was diagnosed with UTROSCT with sarcomatous features. INTERVENTIONS: She initially underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy, followed by second-stage surgery comprising pelvic and para-aortic lymphadenectomy and subtotal omentectomy. OUTCOMES: No postoperative recurrence was observed in the patient in 36 months. LESSONS: In this case, extended radical surgery prevented the development of recurrent disease in a patient with UTROSCT with sarcomatous features. These clinicopathological findings suggest that UTROSCT is associated with several risk factors, including older age, presence of necrosis, lymphovascular invasion, significant nuclear atypia, and significant mitotic activity. This lesion type should be considered malignant and treated with curative intent. |
format | Online Article Text |
id | pubmed-7220453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-72204532020-06-15 Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report Sato, Miho Yano, Mitsutake Sato, Shimpei Aoyagi, Yoko Aso, Saki Matsumoto, Harunobu Yamamoto, Ichiro Nasu, Kaei Medicine (Baltimore) 5600 RATIONALE: The malignant potential and the appropriate treatment of uterine tumor resembling ovarian sex-cord tumor (UTROSCT) is controversial. Although these tumors generally have benign outcomes, several reports have described recurrences, metastases, and deaths associated with this disease. PATIENT CONCERNS: A 57-year-old Japanese woman (gravida 2, para 2) was referred to our hospital for the evaluation and treatment of uterine fibroids. Magnetic resonance imaging revealed a right ovarian mass and multiple fibroids in the uterine myometrium. DIAGNOSES: The patient was diagnosed with UTROSCT with sarcomatous features. INTERVENTIONS: She initially underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy, followed by second-stage surgery comprising pelvic and para-aortic lymphadenectomy and subtotal omentectomy. OUTCOMES: No postoperative recurrence was observed in the patient in 36 months. LESSONS: In this case, extended radical surgery prevented the development of recurrent disease in a patient with UTROSCT with sarcomatous features. These clinicopathological findings suggest that UTROSCT is associated with several risk factors, including older age, presence of necrosis, lymphovascular invasion, significant nuclear atypia, and significant mitotic activity. This lesion type should be considered malignant and treated with curative intent. Wolters Kluwer Health 2020-03-13 /pmc/articles/PMC7220453/ /pubmed/32176042 http://dx.doi.org/10.1097/MD.0000000000019166 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5600 Sato, Miho Yano, Mitsutake Sato, Shimpei Aoyagi, Yoko Aso, Saki Matsumoto, Harunobu Yamamoto, Ichiro Nasu, Kaei Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report |
title | Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report |
title_full | Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report |
title_fullStr | Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report |
title_full_unstemmed | Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report |
title_short | Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) with sarcomatous features without recurrence after extended radical surgery: A case report |
title_sort | uterine tumor resembling ovarian sex-cord tumor (utrosct) with sarcomatous features without recurrence after extended radical surgery: a case report |
topic | 5600 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220453/ https://www.ncbi.nlm.nih.gov/pubmed/32176042 http://dx.doi.org/10.1097/MD.0000000000019166 |
work_keys_str_mv | AT satomiho uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport AT yanomitsutake uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport AT satoshimpei uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport AT aoyagiyoko uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport AT asosaki uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport AT matsumotoharunobu uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport AT yamamotoichiro uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport AT nasukaei uterinetumorresemblingovariansexcordtumorutrosctwithsarcomatousfeatureswithoutrecurrenceafterextendedradicalsurgeryacasereport |