Cargando…

The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy

The new coronavirus SARS-CoV-2 has rapidly spread over the world causing the disease by WHO called COVID-19. This pandemic poses unprecedented stress on the health care system including programs performing allogeneic and autologous hematopoietic cell transplantation (HCT) and cellular therapy such a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ljungman, Per, Mikulska, Malgorzata, de la Camara, Rafael, Basak, Grzegorz W., Chabannon, Christian, Corbacioglu, Selim, Duarte, Rafael, Dolstra, Harry, Lankester, Arjan C., Mohty, Mohamad, Montoto, Silvia, Murray, John, Peffault de Latour, Régis, Snowden, John A., Yakoub-Agha, Ibrahim, Verhoeven, Bregje, Kröger, Nicolaus, Styczynski, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220575/
https://www.ncbi.nlm.nih.gov/pubmed/32404975
http://dx.doi.org/10.1038/s41409-020-0919-0
_version_ 1783533193860743168
author Ljungman, Per
Mikulska, Malgorzata
de la Camara, Rafael
Basak, Grzegorz W.
Chabannon, Christian
Corbacioglu, Selim
Duarte, Rafael
Dolstra, Harry
Lankester, Arjan C.
Mohty, Mohamad
Montoto, Silvia
Murray, John
Peffault de Latour, Régis
Snowden, John A.
Yakoub-Agha, Ibrahim
Verhoeven, Bregje
Kröger, Nicolaus
Styczynski, Jan
author_facet Ljungman, Per
Mikulska, Malgorzata
de la Camara, Rafael
Basak, Grzegorz W.
Chabannon, Christian
Corbacioglu, Selim
Duarte, Rafael
Dolstra, Harry
Lankester, Arjan C.
Mohty, Mohamad
Montoto, Silvia
Murray, John
Peffault de Latour, Régis
Snowden, John A.
Yakoub-Agha, Ibrahim
Verhoeven, Bregje
Kröger, Nicolaus
Styczynski, Jan
author_sort Ljungman, Per
collection PubMed
description The new coronavirus SARS-CoV-2 has rapidly spread over the world causing the disease by WHO called COVID-19. This pandemic poses unprecedented stress on the health care system including programs performing allogeneic and autologous hematopoietic cell transplantation (HCT) and cellular therapy such as with CAR T cells. Risk factors for severe disease include age and predisposing conditions such as cancer. The true impact on stem cell transplant and CAR T-cell recipients in unknown. The European Society for Blood and Marrow Transplantation (EBMT) has therefore developed recommendations for transplant programs and physicians caring for these patients. These guidelines were developed by experts from the Infectious Diseases Working Party and have been endorsed by EBMT’s scientific council and board. This work intends to provide guidelines for transplant centers, management of transplant candidates and recipients, and donor issues until the COVID-19 pandemic has passed.
format Online
Article
Text
id pubmed-7220575
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-72205752020-05-14 The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy Ljungman, Per Mikulska, Malgorzata de la Camara, Rafael Basak, Grzegorz W. Chabannon, Christian Corbacioglu, Selim Duarte, Rafael Dolstra, Harry Lankester, Arjan C. Mohty, Mohamad Montoto, Silvia Murray, John Peffault de Latour, Régis Snowden, John A. Yakoub-Agha, Ibrahim Verhoeven, Bregje Kröger, Nicolaus Styczynski, Jan Bone Marrow Transplant Perspective The new coronavirus SARS-CoV-2 has rapidly spread over the world causing the disease by WHO called COVID-19. This pandemic poses unprecedented stress on the health care system including programs performing allogeneic and autologous hematopoietic cell transplantation (HCT) and cellular therapy such as with CAR T cells. Risk factors for severe disease include age and predisposing conditions such as cancer. The true impact on stem cell transplant and CAR T-cell recipients in unknown. The European Society for Blood and Marrow Transplantation (EBMT) has therefore developed recommendations for transplant programs and physicians caring for these patients. These guidelines were developed by experts from the Infectious Diseases Working Party and have been endorsed by EBMT’s scientific council and board. This work intends to provide guidelines for transplant centers, management of transplant candidates and recipients, and donor issues until the COVID-19 pandemic has passed. Nature Publishing Group UK 2020-05-13 2020 /pmc/articles/PMC7220575/ /pubmed/32404975 http://dx.doi.org/10.1038/s41409-020-0919-0 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Perspective
Ljungman, Per
Mikulska, Malgorzata
de la Camara, Rafael
Basak, Grzegorz W.
Chabannon, Christian
Corbacioglu, Selim
Duarte, Rafael
Dolstra, Harry
Lankester, Arjan C.
Mohty, Mohamad
Montoto, Silvia
Murray, John
Peffault de Latour, Régis
Snowden, John A.
Yakoub-Agha, Ibrahim
Verhoeven, Bregje
Kröger, Nicolaus
Styczynski, Jan
The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
title The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
title_full The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
title_fullStr The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
title_full_unstemmed The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
title_short The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy
title_sort challenge of covid-19 and hematopoietic cell transplantation; ebmt recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing car t-cell therapy
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220575/
https://www.ncbi.nlm.nih.gov/pubmed/32404975
http://dx.doi.org/10.1038/s41409-020-0919-0
work_keys_str_mv AT ljungmanper thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT mikulskamalgorzata thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT delacamararafael thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT basakgrzegorzw thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT chabannonchristian thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT corbaciogluselim thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT duarterafael thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT dolstraharry thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT lankesterarjanc thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT mohtymohamad thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT montotosilvia thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT murrayjohn thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT peffaultdelatourregis thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT snowdenjohna thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT yakoubaghaibrahim thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT verhoevenbregje thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT krogernicolaus thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT styczynskijan thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT thechallengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT ljungmanper challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT mikulskamalgorzata challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT delacamararafael challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT basakgrzegorzw challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT chabannonchristian challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT corbaciogluselim challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT duarterafael challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT dolstraharry challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT lankesterarjanc challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT mohtymohamad challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT montotosilvia challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT murrayjohn challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT peffaultdelatourregis challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT snowdenjohna challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT yakoubaghaibrahim challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT verhoevenbregje challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT krogernicolaus challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT styczynskijan challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy
AT challengeofcovid19andhematopoieticcelltransplantationebmtrecommendationsformanagementofhematopoieticcelltransplantrecipientstheirdonorsandpatientsundergoingcartcelltherapy