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Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study
Congenital diaphragmatic eventration (CDE) and congenital diaphragmatic hernia (CDH) with or without hernia sac are three different types of congenital diaphragmatic malformations, which this study evaluates. All surgically treated patients with CDE or Bochdalek type CDH between 2000 and 2016 were i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220865/ https://www.ncbi.nlm.nih.gov/pubmed/31965300 http://dx.doi.org/10.1007/s00431-020-03576-w |
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author | Heiwegen, Kim van Heijst, Arno FJ Daniels-Scharbatke, Horst van Peperstraten, Michelle CP de Blaauw, Ivo Botden, Sanne MBI |
author_facet | Heiwegen, Kim van Heijst, Arno FJ Daniels-Scharbatke, Horst van Peperstraten, Michelle CP de Blaauw, Ivo Botden, Sanne MBI |
author_sort | Heiwegen, Kim |
collection | PubMed |
description | Congenital diaphragmatic eventration (CDE) and congenital diaphragmatic hernia (CDH) with or without hernia sac are three different types of congenital diaphragmatic malformations, which this study evaluates. All surgically treated patients with CDE or Bochdalek type CDH between 2000 and 2016 were included in this retrospective analysis. Demographics, CDH-characteristics, treatment, and clinical outcome were evaluated. In total, 200 patients were included. Patients with an eventration or hernia sac had no significant differences and were compared as patients without a true defect to patients with a true defect. The 1-year survival of patients with a true defect was significantly lower than patients with no true defect (76% versus 97%, p = 0.001). CDH with no true defect had significantly better short-term outcomes than CDH with true defect requiring patch repair. However, at 30 days, they more often required oxygen supplementation (46% versus 26%, p = 0.03) and had a higher recurrence rate (8% versus 0%, p = 0.006) (three eventration and two hernia sac patients). Conclusion: Patients without a true defect seem to have a more similar clinical outcome than CDH patients with a true defect, with a better survival. However, the recurrence rate and duration of oxygen supplementation at 30 days are higher than CDH patients with a true defect. |
format | Online Article Text |
id | pubmed-7220865 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-72208652020-05-14 Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study Heiwegen, Kim van Heijst, Arno FJ Daniels-Scharbatke, Horst van Peperstraten, Michelle CP de Blaauw, Ivo Botden, Sanne MBI Eur J Pediatr Original Article Congenital diaphragmatic eventration (CDE) and congenital diaphragmatic hernia (CDH) with or without hernia sac are three different types of congenital diaphragmatic malformations, which this study evaluates. All surgically treated patients with CDE or Bochdalek type CDH between 2000 and 2016 were included in this retrospective analysis. Demographics, CDH-characteristics, treatment, and clinical outcome were evaluated. In total, 200 patients were included. Patients with an eventration or hernia sac had no significant differences and were compared as patients without a true defect to patients with a true defect. The 1-year survival of patients with a true defect was significantly lower than patients with no true defect (76% versus 97%, p = 0.001). CDH with no true defect had significantly better short-term outcomes than CDH with true defect requiring patch repair. However, at 30 days, they more often required oxygen supplementation (46% versus 26%, p = 0.03) and had a higher recurrence rate (8% versus 0%, p = 0.006) (three eventration and two hernia sac patients). Conclusion: Patients without a true defect seem to have a more similar clinical outcome than CDH patients with a true defect, with a better survival. However, the recurrence rate and duration of oxygen supplementation at 30 days are higher than CDH patients with a true defect. Springer Berlin Heidelberg 2020-01-22 2020 /pmc/articles/PMC7220865/ /pubmed/31965300 http://dx.doi.org/10.1007/s00431-020-03576-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Original Article Heiwegen, Kim van Heijst, Arno FJ Daniels-Scharbatke, Horst van Peperstraten, Michelle CP de Blaauw, Ivo Botden, Sanne MBI Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study |
title | Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study |
title_full | Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study |
title_fullStr | Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study |
title_full_unstemmed | Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study |
title_short | Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study |
title_sort | congenital diaphragmatic eventration and hernia sac compared to cdh with true defects: a retrospective cohort study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220865/ https://www.ncbi.nlm.nih.gov/pubmed/31965300 http://dx.doi.org/10.1007/s00431-020-03576-w |
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