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TMEM16A drives renal cyst growth by augmenting Ca(2+) signaling in M1 cells

ABSTRACT: Polycystic kidney disease (PKD) leads to continuous decline of renal function by growth of renal cysts. Enhanced proliferation and transepithelial chloride secretion through cystic fibrosis transmembrane conductance regulator (CFTR) and Ca(2+)-activated TMEM16A Cl(−) channels is thought to...

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Detalles Bibliográficos
Autores principales:	Cabrita, Ines, Buchholz, Björn, Schreiber, Rainer, Kunzelmann, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220898/ https://www.ncbi.nlm.nih.gov/pubmed/32185407 http://dx.doi.org/10.1007/s00109-020-01894-y

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