The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent

Most systemic lupus erythematosus (SLE) patients are photosensitive and ultraviolet B light (UVB) exposure worsens cutaneous disease and precipitates systemic flares of disease. The pathogenic link between skin disease and systemic exacerbations in SLE remains elusive. In an acute model of UVB-trigg...

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Detalles Bibliográficos
Autores principales: Skopelja-Gardner, Sladjana, An, Jie, Tai, Joyce, Tanaka, Lena, Sun, Xizhang, Hermanson, Payton, Baum, Rebecca, Kawasumi, Masaoki, Green, Richard, Gale Jr., Michael, Kalus, Andrea, Werth, Victoria P., Elkon, Keith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220927/
https://www.ncbi.nlm.nih.gov/pubmed/32404939
http://dx.doi.org/10.1038/s41598-020-64865-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220927/
https://www.ncbi.nlm.nih.gov/pubmed/32404939
http://dx.doi.org/10.1038/s41598-020-64865-w

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