Advanced Single-Cell Mapping Reveals that in hESC Cardiomyocytes Contraction Kinetics and Action Potential Are Independent of Myosin Isoform

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) represent an attractive model to investigate CM function and disease mechanisms. One characteristic marker of ventricular specificity of human CMs is expression of the ventricular, slow β-myosin heavy chain (MyHC), as opposed to the atria...

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Detalles Bibliográficos
Autores principales: Weber, Natalie, Kowalski, Kathrin, Holler, Tim, Radocaj, Ante, Fischer, Martin, Thiemann, Stefan, de la Roche, Jeanne, Schwanke, Kristin, Piep, Birgit, Peschel, Neele, Krumm, Uwe, Lingk, Alexander, Wendland, Meike, Greten, Stephan, Schmitto, Jan Dieter, Ismail, Issam, Warnecke, Gregor, Zywietz, Urs, Chichkov, Boris, Meißner, Joachim, Haverich, Axel, Martin, Ulrich, Brenner, Bernhard, Zweigerdt, Robert, Kraft, Theresia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220955/
https://www.ncbi.nlm.nih.gov/pubmed/32302556
http://dx.doi.org/10.1016/j.stemcr.2020.03.015

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