Developmental IL-6 Exposure Favors Production of PDGF-Responsive Multipotential Progenitors at the Expense of Neural Stem Cells and Other Progenitors

Interleukin-6 (IL-6) is increased in maternal serum and amniotic fluid of children subsequently diagnosed with autism spectrum disorders. However, it is not clear how increased IL-6 alters brain development. Here, we show that IL-6 increases the prevalence of a specific platelet-derived growth facto...

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Detalles Bibliográficos
Autores principales: Kumari, Ekta, Velloso, Fernando J., Nasuhidehnavi, Azadeh, Somasundaram, Aditya, Savanur, Vibha H., Buono, Krista D., Levison, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220986/
https://www.ncbi.nlm.nih.gov/pubmed/32302560
http://dx.doi.org/10.1016/j.stemcr.2020.03.019

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