Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System

Studies of hematopoietic stem cell (HSC) development from pre-HSC-producing hemogenic endothelial cells (HECs) are hampered by the rarity of these cells and the presence of other cell types with overlapping marker expression profiles. We generated a Tg(Runx1-mKO2; Ly6a-GFP) dual reporter mouse to vi...

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Detalles Bibliográficos
Autores principales: Chen, Michael J., Lummertz da Rocha, Edroaldo, Cahan, Patrick, Kubaczka, Caroline, Hunter, Phoebe, Sousa, Patricia, Mullin, Nathaniel K., Fujiwara, Yuko, Nguyen, Minh, Tan, Yuqi, Landry, Samuel, Han, Areum, Yang, Song, Lu, Yi-Fen, Jha, Deepak Kumar, Vo, Linda T., Zhou, Yi, North, Trista E., Zon, Leonard I., Daley, George Q., Schlaeger, Thorsten M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220988/
https://www.ncbi.nlm.nih.gov/pubmed/32302558
http://dx.doi.org/10.1016/j.stemcr.2020.03.020

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