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Development, validation and regulatory acceptance of improved purification and simplified quality control of [(13)N] Ammonia

BACKGROUND: [(13)N]Ammonia is a cyclotron produced myocardial perfusion imaging agent. With the development of high-yielding [(13)N]ammonia cyclotron targets using a solution of 5 mM ethanol in water, there was a need to develop and validate an automated purification and formulation system for [(13)...

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Detalles Bibliográficos
Autores principales: Yokell, Daniel L., Rice, Peter A., Neelamegam, Ramesh, El Fakhri, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221112/
https://www.ncbi.nlm.nih.gov/pubmed/32405797
http://dx.doi.org/10.1186/s41181-020-00097-7