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Development, validation and regulatory acceptance of improved purification and simplified quality control of [(13)N] Ammonia
BACKGROUND: [(13)N]Ammonia is a cyclotron produced myocardial perfusion imaging agent. With the development of high-yielding [(13)N]ammonia cyclotron targets using a solution of 5 mM ethanol in water, there was a need to develop and validate an automated purification and formulation system for [(13)...
Autores principales: | Yokell, Daniel L., Rice, Peter A., Neelamegam, Ramesh, El Fakhri, Georges |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221112/ https://www.ncbi.nlm.nih.gov/pubmed/32405797 http://dx.doi.org/10.1186/s41181-020-00097-7 |
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