A Hybrid Peptide DEFB-TP5 Expressed in Methylotrophic Yeast Neutralizes LPS With Potent Anti-inflammatory Activities

DEFB-TP5 is a novel auspicious health-beneficial peptide derivative from two naturally occurring peptides, β-Defensin (DEFB) and thymopentin (TP5), and shows strong anti-inflammatory activity and binds to LPS without cytotoxicity and hemolytic effect. Furthermore, the application of DEFB-TP5 peptide...

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Detalles Bibliográficos
Autores principales: Ahmad, Baseer, Li, Zhongxuan, Hanif, Quratulain, Hu, Qingyong, Wei, Xubiao, Zhang, Lulu, Khan, Shahzad Akbar, Aihemaiti, Maierhaba, Gulzar, Huma, Shahid, Muhammad, Si, Dayong, Zhang, Rijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221121/
https://www.ncbi.nlm.nih.gov/pubmed/32457599
http://dx.doi.org/10.3389/fphar.2020.00461

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