A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes

Listeria monocytogenes is a Gram-positive pathogen able to cause severe human infections. Its major virulence regulator is the transcriptional activator PrfA, a member of the Crp/Fnr family of transcriptional regulators. To establish a successful L. monocytogenes infection, the PrfA protein needs to...

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Detalles Bibliográficos
Autores principales: Hansen, Sabine, Hall, Michael, Grundström, Christin, Brännström, Kristoffer, Sauer-Eriksson, A. Elisabeth, Johansson, Jörgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221254/
https://www.ncbi.nlm.nih.gov/pubmed/32179627
http://dx.doi.org/10.1128/JB.00115-20

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