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The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training

Transcranial direct current stimulation (tDCS) has been shown to enhance the efficacy and generalisation of working memory (WM) training, but there has been little systematic investigation into how coupling task-specific WM training with stimulation impacts more specifically on transfer to untrained...

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Autores principales: Byrne, Elizabeth M., Ewbank, Michael P., Gathercole, Susan E., Holmes, Joni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221346/
https://www.ncbi.nlm.nih.gov/pubmed/32298870
http://dx.doi.org/10.1016/j.bandc.2020.105552
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author Byrne, Elizabeth M.
Ewbank, Michael P.
Gathercole, Susan E.
Holmes, Joni
author_facet Byrne, Elizabeth M.
Ewbank, Michael P.
Gathercole, Susan E.
Holmes, Joni
author_sort Byrne, Elizabeth M.
collection PubMed
description Transcranial direct current stimulation (tDCS) has been shown to enhance the efficacy and generalisation of working memory (WM) training, but there has been little systematic investigation into how coupling task-specific WM training with stimulation impacts more specifically on transfer to untrained tasks. This randomised controlled trial investigated the boundary conditions to transfer by testing firstly whether the benefits of training on backward digit recall (BDR) extend to untrained backward recall tasks and n-back tasks with different materials, and secondly which, if any, form of transfer is enhanced by tDCS. Forty-eight participants were allocated to one of three conditions: BDR training with anodal (10 min, 1 mA) or sham tDCS, or visual search training with sham tDCS, applied over the left dorsolateral prefrontal cortex. Transfer was assessed on within- (backward recall with digits, letters, and spatial locations) and cross-paradigm (n-back with digits and letters) transfer tests following three sessions of training and stimulation. On-task training gains were found, with transfer to other backward span but not n-back tasks. There was little evidence that tDCS enhanced on-task training or transfer. These findings indicate that training enhances paradigm-specific processes within WM, but that tDCS does not enhance these gains.
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spelling pubmed-72213462020-06-01 The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training Byrne, Elizabeth M. Ewbank, Michael P. Gathercole, Susan E. Holmes, Joni Brain Cogn Article Transcranial direct current stimulation (tDCS) has been shown to enhance the efficacy and generalisation of working memory (WM) training, but there has been little systematic investigation into how coupling task-specific WM training with stimulation impacts more specifically on transfer to untrained tasks. This randomised controlled trial investigated the boundary conditions to transfer by testing firstly whether the benefits of training on backward digit recall (BDR) extend to untrained backward recall tasks and n-back tasks with different materials, and secondly which, if any, form of transfer is enhanced by tDCS. Forty-eight participants were allocated to one of three conditions: BDR training with anodal (10 min, 1 mA) or sham tDCS, or visual search training with sham tDCS, applied over the left dorsolateral prefrontal cortex. Transfer was assessed on within- (backward recall with digits, letters, and spatial locations) and cross-paradigm (n-back with digits and letters) transfer tests following three sessions of training and stimulation. On-task training gains were found, with transfer to other backward span but not n-back tasks. There was little evidence that tDCS enhanced on-task training or transfer. These findings indicate that training enhances paradigm-specific processes within WM, but that tDCS does not enhance these gains. Academic Press 2020-06 /pmc/articles/PMC7221346/ /pubmed/32298870 http://dx.doi.org/10.1016/j.bandc.2020.105552 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Byrne, Elizabeth M.
Ewbank, Michael P.
Gathercole, Susan E.
Holmes, Joni
The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training
title The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training
title_full The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training
title_fullStr The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training
title_full_unstemmed The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training
title_short The effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training
title_sort effects of transcranial direct current stimulation on within- and cross-paradigm transfer following multi-session backward recall training
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221346/
https://www.ncbi.nlm.nih.gov/pubmed/32298870
http://dx.doi.org/10.1016/j.bandc.2020.105552
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