Functional informed genome‐wide interaction analysis of body mass index, diabetes and colorectal cancer risk

BACKGROUND: Body mass index (BMI) and diabetes are established risk factors for colorectal cancer (CRC), likely through perturbations in metabolic traits (e.g. insulin resistance and glucose homeostasis). Identification of interactions between variation in genes and these metabolic risk factors may...

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Autores principales: Xia, Zhiyu, Su, Yu‐Ru, Petersen, Paneen, Qi, Lihong, Kim, Andre E., Figueiredo, Jane C., Lin, Yi, Nan, Hongmei, Sakoda, Lori C., Albanes, Demetrius, Berndt, Sonja I., Bézieau, Stéphane, Bien, Stephanie, Buchanan, Daniel D., Casey, Graham, Chan, Andrew T., Conti, David V., Drew, David A., Gallinger, Steven J., Gauderman, W. James, Giles, Graham G., Gruber, Stephen B., Gunter, Marc J., Hoffmeister, Michael, Jenkins, Mark A., Joshi, Amit D., Le Marchand, Loic, Lewinger, Juan P., Li, Li, Lindor, Noralane M., Moreno, Victor, Murphy, Neil, Nassir, Rami, Newcomb, Polly A., Ogino, Shuji, Rennert, Gad, Song, Mingyang, Wang, Xiaoliang, Wolk, Alicja, Woods, Michael O., Brenner, Hermann, White, Emily, Slattery, Martha L., Giovannucci, Edward L., Chang‐Claude, Jenny, Pharoah, Paul D. P., Hsu, Li, Campbell, Peter T., Peters, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221445/
https://www.ncbi.nlm.nih.gov/pubmed/32207560
http://dx.doi.org/10.1002/cam4.2971

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