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Model of a Queuing Approach for Patient Accrual in Phase 1 Oncology Studies
IMPORTANCE: Phase 1 cancer studies, which guide dose selection for subsequent studies, are almost 3 times more prevalent than phase 3 studies and have a median study duration considerably longer than 2 years, which constitutes a major component of drug development time. OBJECTIVE: To discern a metho...
Autores principales: | Frankel, Paul H., Chung, Vincent, Tuscano, Joseph, Siddiqi, Tanya, Sampath, Sagus, Longmate, Jeffrey, Groshen, Susan, Newman, Edward M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221509/ https://www.ncbi.nlm.nih.gov/pubmed/32401317 http://dx.doi.org/10.1001/jamanetworkopen.2020.4787 |
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