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Insights on Ultrafiltration-Based Separation for the Purification and Quantification of Methotrexate in Nanocarriers
The evaluation of encapsulation efficiency is a regulatory requirement for the characterization of drug delivery systems. However, the difficulties in efficiently separating nanomedicines from the free drug may compromise the achievement of accurate determinations. Herein, ultrafiltration was exploi...
Autores principales: | Marques, Sara S., Ramos, Inês I., Fernandes, Sara R., Barreiros, Luisa, Lima, Sofia A. C., Reis, Salette, Domingues, M. Rosário M., Segundo, Marcela A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221554/ https://www.ncbi.nlm.nih.gov/pubmed/32325744 http://dx.doi.org/10.3390/molecules25081879 |
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