Cargando…
Multitarget Approach to Drug Candidates against Alzheimer’s Disease Related to AChE, SERT, BACE1 and GSK3β Protein Targets
Alzheimer’s disease is a neurodegenerative condition for which currently there are no drugs that can cure its devastating impact on human brain function. Although there are therapeutics that are being used in contemporary medicine for treatment against Alzheimer’s disease, new and more effective dru...
Autores principales: | Ivanova, Larisa, Karelson, Mati, Dobchev, Dimitar A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221701/ https://www.ncbi.nlm.nih.gov/pubmed/32316402 http://dx.doi.org/10.3390/molecules25081846 |
Ejemplares similares
-
Identification of Natural Compounds against Neurodegenerative Diseases Using In Silico Techniques
por: Ivanova, Larisa, et al.
Publicado: (2018) -
New compounds from heterocyclic amines scaffold with multitarget inhibitory activity on Aβ aggregation, AChE, and BACE1 in the Alzheimer disease
por: García Marín, Iohanan Daniel, et al.
Publicado: (2022) -
Design, Synthesis,
and Biological Evaluation of Notopterol
Derivatives as Triple Inhibitors of AChE/BACE1/GSK3β for the
Treatment of Alzheimer’s Disease
por: Wang, Nan, et al.
Publicado: (2022) -
Correction to Design, Synthesis, and Biological Evaluation
of Notopterol Derivatives as Triple Inhibitors of AChE/BACE1/GSK3β
for the Treatment of Alzheimer’s Disease
por: Wang, Nan, et al.
Publicado: (2022) -
Multitargeted Virtual Screening and Molecular Simulation of Natural Product-like Compounds against GSK3β, NMDA-Receptor, and BACE-1 for the Management of Alzheimer’s Disease
por: Iqbal, Danish, et al.
Publicado: (2023)