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Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees
In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads to their increased susceptibility to pathogens. Ascosphaera apis is a dangerous entomopathogenic fungus, a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221740/ https://www.ncbi.nlm.nih.gov/pubmed/32331472 http://dx.doi.org/10.3390/molecules25081954 |
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author | Yaremenko, Ivan A. Syromyatnikov, Mikhail Y. Radulov, Peter S. Belyakova, Yulia Yu. Fomenkov, Dmitriy I. Popov, Vasily N. Terent’ev, Alexander O. |
author_facet | Yaremenko, Ivan A. Syromyatnikov, Mikhail Y. Radulov, Peter S. Belyakova, Yulia Yu. Fomenkov, Dmitriy I. Popov, Vasily N. Terent’ev, Alexander O. |
author_sort | Yaremenko, Ivan A. |
collection | PubMed |
description | In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads to their increased susceptibility to pathogens. Ascosphaera apis is a dangerous entomopathogenic fungus, afflicting both honeybees and bumblebees. We investigated fungicide activity of cyclic synthetic peroxides against A. apis isolated from Bombus terrestris L. The peroxides exhibited high mycelium growth inhibition of A. apis up to 94–100% at concentration 30 mg/L. EC(50) values were determined for the most active peroxides. Two peroxides showed higher antifungal activity against A. apis than the commercial fungicide Triadimefon. The studied peroxides did not reduce the ability of bumblebees to fly and did not lead to the death of bumblebees. A new field of application for peroxides was disclosed. |
format | Online Article Text |
id | pubmed-7221740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72217402020-05-21 Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees Yaremenko, Ivan A. Syromyatnikov, Mikhail Y. Radulov, Peter S. Belyakova, Yulia Yu. Fomenkov, Dmitriy I. Popov, Vasily N. Terent’ev, Alexander O. Molecules Article In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads to their increased susceptibility to pathogens. Ascosphaera apis is a dangerous entomopathogenic fungus, afflicting both honeybees and bumblebees. We investigated fungicide activity of cyclic synthetic peroxides against A. apis isolated from Bombus terrestris L. The peroxides exhibited high mycelium growth inhibition of A. apis up to 94–100% at concentration 30 mg/L. EC(50) values were determined for the most active peroxides. Two peroxides showed higher antifungal activity against A. apis than the commercial fungicide Triadimefon. The studied peroxides did not reduce the ability of bumblebees to fly and did not lead to the death of bumblebees. A new field of application for peroxides was disclosed. MDPI 2020-04-22 /pmc/articles/PMC7221740/ /pubmed/32331472 http://dx.doi.org/10.3390/molecules25081954 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yaremenko, Ivan A. Syromyatnikov, Mikhail Y. Radulov, Peter S. Belyakova, Yulia Yu. Fomenkov, Dmitriy I. Popov, Vasily N. Terent’ev, Alexander O. Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees |
title | Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees |
title_full | Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees |
title_fullStr | Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees |
title_full_unstemmed | Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees |
title_short | Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees |
title_sort | cyclic synthetic peroxides inhibit growth of entomopathogenic fungus ascosphaera apis without toxic effect on bumblebees |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221740/ https://www.ncbi.nlm.nih.gov/pubmed/32331472 http://dx.doi.org/10.3390/molecules25081954 |
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