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The Hydrophobic Ligands Entry and Exit from the GPCR Binding Site-SMD and SuMD Simulations

Most G protein-coupled receptors that bind the hydrophobic ligands (lipid receptors and steroid receptors) belong to the most populated class A (rhodopsin-like) of these receptors. Typical examples of lipid receptors are: rhodopsin, cannabinoid (CB), sphingosine-1-phosphate (S1P) and lysophosphatidi...

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Detalles Bibliográficos
Autores principales:	Jakowiecki, Jakub, Orzeł, Urszula, Chawananon, Sathapana, Miszta, Przemysław, Filipek, Sławomir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221835/ https://www.ncbi.nlm.nih.gov/pubmed/32326322 http://dx.doi.org/10.3390/molecules25081930

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