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Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry Method for Pharmacokinetic Evaluation of 7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranon in Rats

Recently, potent neuroprotective and anti-diabetic effects of 7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone (ECN), a sesquiterpenoid isolated from Tussilago farfara Linnaeus, have been elucidated. To facilitate further pre-clinical evaluation in rats, an analyt...

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Detalles Bibliográficos
Autores principales:	Kang, Nae-Won, Lee, Jae-Young, Song, Kwangho, Kim, Min-Hwan, Yoon, Soyeon, Nguyen, Duy-Thuc, Kim, Sungho, Kim, Yeong Shik, Kim, Dae-Duk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221868/ https://www.ncbi.nlm.nih.gov/pubmed/32294941 http://dx.doi.org/10.3390/molecules25081774

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