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In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against Leishmania donovani and Trypanosoma brucei

Kinetoplastid parasites, including Leishmania and Trypanosoma spp., are life threatening pathogens with a worldwide distribution. Next-generation therapeutics for treatment are needed as current treatments have limitations, such as toxicity and drug resistance. In this study, we examined the activit...

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Detalles Bibliográficos
Autores principales: Phan, Trong-Nhat, Baek, Kyung-Hwa, Lee, Nakyung, Byun, Soo Young, Shum, David, No, Joo Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221892/
https://www.ncbi.nlm.nih.gov/pubmed/32340370
http://dx.doi.org/10.3390/molecules25081980