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Internalized FGF-2-Loaded Nanoparticles Increase Nuclear ERK1/2 Content and Result in Lung Cancer Cell Death
Innovative cancer treatments, which improve adjuvant therapy and reduce adverse events, are desperately needed. Nanoparticles provide controlled intracellular biomolecule delivery in the absence of activating external cell surface receptors. Prior reports suggest that intracrine signaling, following...
Autores principales: | Miao, Tianxin, Little, Andrew C., Aronshtam, Alexander, Marquis, Taylor, Fenn, Spencer L., Hristova, Milena, Krementsov, Dimitry N., van der Vliet, Albert, Spees, Jeffrey L., Oldinski, Rachael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221911/ https://www.ncbi.nlm.nih.gov/pubmed/32230722 http://dx.doi.org/10.3390/nano10040612 |
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