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Recent Advances in the Stereoselective Total Synthesis of Natural Pyranones Having Long Side Chains

Pyranone natural products have attracted great attention in recent years from chemists and biologists due to their fascinating stereoisomeric structural features and impressive bioactivities. A large number of stereoselective total syntheses of these compounds have been described in the literature....

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Detalles Bibliográficos
Autores principales: Avula, Satya Kumar, Das, Biswanath, Csuk, Rene, Al-Rawahi, Ahmed, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221952/
https://www.ncbi.nlm.nih.gov/pubmed/32326105
http://dx.doi.org/10.3390/molecules25081905
Descripción
Sumario:Pyranone natural products have attracted great attention in recent years from chemists and biologists due to their fascinating stereoisomeric structural features and impressive bioactivities. A large number of stereoselective total syntheses of these compounds have been described in the literature. The natural pyranones with long side chains have recently received significant importance in the synthetic field. In the present article, we aim to review the modern progress of the stereoselective total syntheses of these natural pyranones containing long-chain substituents.