Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View

Enantiomeric separation is a key step in the development of a new chiral drug. Preparative liquid chromatography (LC) continues to be the technique of choice either during the drug discovery process, to achieve a few milligrams, or to a scale-up during the clinical trial, needing kilograms of materi...

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Detalles Bibliográficos
Autores principales: Pinto, Madalena M.M., Fernandes, Carla, Tiritan, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221958/
https://www.ncbi.nlm.nih.gov/pubmed/32326326
http://dx.doi.org/10.3390/molecules25081931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221958/
https://www.ncbi.nlm.nih.gov/pubmed/32326326
http://dx.doi.org/10.3390/molecules25081931

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