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Aesculus hippocastanum L. Extract Does Not Induce Fibroblast to Myofibroblast Conversion but Increases Extracellular Matrix Production In Vitro Leading to Increased Wound Tensile Strength in Rats

The ability of horse chestnut extract (HCE) to induce contraction force in fibroblasts, a process with remarkable significance in skin repair, motivated us to evaluate its wound healing potential in a series of experiments. In the in vitro study of the ability of human dermal fibroblasts to form myo...

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Detalles Bibliográficos
Autores principales: Kováč, Ivan, Melegová, Nikola, Čoma, Matúš, Takáč, Peter, Kováčová, Katarína, Hollý, Martin, Ďurkáč, Ján, Urban, Lukáš, Gurbáľová, Miriam, Švajdlenka, Emil, Mojžišová, Gabriela, Zajíček, Robert, Szabo, Pavol, Mučaji, Pavel, Gál, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221972/
https://www.ncbi.nlm.nih.gov/pubmed/32331226
http://dx.doi.org/10.3390/molecules25081917