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Predicting sporadic Alzheimer’s disease progression via inherited Alzheimer’s disease-informed machine-learning
INTRODUCTION: Developing cross-validated multi-biomarker models for the prediction of the rate of cognitive decline in Alzheimer’s disease (AD) is a critical yet unmet clinical challenge. METHODS: We applied support vector regression to AD biomarkers derived from cerebrospinal fluid, structural magn...
Autores principales: | Franzmeier, Nicolai, Koutsouleris, Nikolaos, Benzinger, Tammie, Goate, Alison, Karch, Celeste M., Fagan, Anne M., McDade, Eric, Duering, Marco, Dichgans, Martin, Levin, Johannes, Gordon, Brian A., Lim, Yen Ying, Masters, Colin L., Rossor, Martin, Fox, Nick C., O’Connor, Antoinette, Chhatwal, Jasmeer, Salloway, Stephen, Danek, Adrian, Hassenstab, Jason, Schofield, Peter R., Morris, John C., Bateman, Randall J., Ewers, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222030/ https://www.ncbi.nlm.nih.gov/pubmed/32043733 http://dx.doi.org/10.1002/alz.12032 |
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