Cargando…
PCSK9 Regulates Nox2-Mediated Platelet Activation via CD36 Receptor in Patients with Atrial Fibrillation
Background: High levels of proprotein convertase subtilisin/kexin 9 (PCSK9) is predictive of cardiovascular events (CVEs) in atrial fibrillation (AF). We hypothesized that PCSK9 may directly induce platelet activation (PA). Methods: We measured platelet aggregation, recruitment, Thromboxane B2 (TxB2...
Autores principales: | Cammisotto, Vittoria, Pastori, Daniele, Nocella, Cristina, Bartimoccia, Simona, Castellani, Valentina, Marchese, Cinzia, Sili Scavalli, Antonio, Ettorre, Evaristo, Viceconte, Nicola, Violi, Francesco, Pignatelli, Pasquale, Carnevale, Roberto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222182/ https://www.ncbi.nlm.nih.gov/pubmed/32252393 http://dx.doi.org/10.3390/antiox9040296 |
Ejemplares similares
-
Digoxin and Platelet Activation in Patients With Atrial Fibrillation: In Vivo and In Vitro Study
por: Pastori, Daniele, et al.
Publicado: (2018) -
Gut-derived low-grade endotoxaemia, atherothrombosis and cardiovascular disease
por: Violi, Francesco, et al.
Publicado: (2022) -
Circulating Lipopolysaccharides and Impaired Antioxidant Status in Patients With Atrial Fibrillation. Data From the ATHERO-AF Study
por: Menichelli, Danilo, et al.
Publicado: (2021) -
Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies
por: Nocella, Cristina, et al.
Publicado: (2023) -
Age-related increase of thromboxane B(2) and risk of cardiovascular disease in atrial fibrillation
por: Pastori, Daniele, et al.
Publicado: (2016)