Ezetimibe Prevents Ischemia/Reperfusion-Induced Oxidative Stress and Up-Regulates Nrf2/ARE and UPR Signaling Pathways

Background: While reperfusion is crucial for survival after an episode of ischemia, it also causes oxidative stress. Nuclear factor-E2-related factor 2 (Nrf2) and unfolded protein response (UPR) are protective against oxidative stress and endoplasmic reticulum (ER) stress. Ezetimibe, a cholesterol a...

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Detalles Bibliográficos
Autores principales: Peserico, Denise, Stranieri, Chiara, Garbin, Ulisse, Mozzini C, Chiara, Danese, Elisa, Cominacini, Luciano, Fratta Pasini, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222361/
https://www.ncbi.nlm.nih.gov/pubmed/32340270
http://dx.doi.org/10.3390/antiox9040349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222361/
https://www.ncbi.nlm.nih.gov/pubmed/32340270
http://dx.doi.org/10.3390/antiox9040349

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