Cargando…

Proteomic analysis revealed T cell hyporesponsiveness induced by Haemonchus contortus excretory and secretory proteins

Haemonchus contortus has evolved highly integrated and sophisticated mechanisms to promote coexistence with hosts. The excretory-secretory (ES) products generated by this parasite contribute to the regulation of the host immune response to facilitate immune evasion and induce chronicity, but the pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Mingmin, Tian, Xiaowei, Yang, Zhang, Wang, Wenjuan, Tian, Ai-Ling, Li, Charles, Yan, Ruofeng, Xu, Lixin, Song, Xiaokai, Li, Xiangrui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222441/ https://www.ncbi.nlm.nih.gov/pubmed/32404195 http://dx.doi.org/10.1186/s13567-020-00790-0

Ejemplares similares

Protection studies of an excretory–secretory protein HcABHD against Haemonchus contortus infection
por: Lu, Mingmin, et al.
Publicado: (2021)

HcTTR: a novel antagonist against goat interleukin 4 derived from the excretory and secretory products of Haemonchus contortus
por: Tian, XiaoWei, et al.
Publicado: (2019)

Identification of excretory and secretory proteins from Haemonchus contortus inducing a Th9 immune response in goats
por: Liang, Meng, et al.
Publicado: (2022)

Proteomic Analysis of the Excretory and Secretory Proteins of Haemonchus contortus (HcESP) Binding to Goat PBMCs In Vivo Revealed Stage-Specific Binding Profiles
por: Gadahi, Javaid Ali, et al.
Publicado: (2016)

A Novel α/β Hydrolase Domain Protein Derived From Haemonchus contortus Acts at the Parasite-Host Interface
por: Lu, Mingmin, et al.
Publicado: (2020)

Characterization of Haemonchus contortus Excretory/Secretory Antigen (ES-15) and Its Modulatory Functions on Goat Immune Cells In Vitro
por: Ehsan, Muhammad, et al.
Publicado: (2020)

Immunization With Recombinant Haemonchus contortus Y75B8A.8 Partially Protects Local Crossbred Female Goats From Haemonchus contortus Infection
por: Tian, Xiaowei, et al.
Publicado: (2022)

Unveiling the immunomodulatory properties of Haemonchus contortus adhesion regulating molecule 1 interacting with goat T cells
por: Lu, Mingmin, et al.
Publicado: (2020)

Immunomodulatory dynamics of excretory and secretory products on Th9 immune response during Haemonchus contortus infection in goat
por: Memon, Muhammad Ali, et al.
Publicado: (2020)

Tropomyosin: An Excretory/Secretory Protein from Haemonchus contortus Mediates the Immuno-Suppressive Potential of Goat Peripheral Blood Mononuclear Cells In Vitro
por: Ehsan, Muhammad, et al.
Publicado: (2020)

Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus
por: Wen, Zhaohai, et al.
Publicado: (2022)

Recombinant Haemonchus contortus 24 kDa excretory/secretory protein (rHcES-24) modulate the immune functions of goat PBMCs in vitro
por: Gadahi, Javaid Ali, et al.
Publicado: (2016)

Adhesion-Regulating Molecule from Haemonchus contortus: Potential Antigen for Diagnosis of Early Infection in Goats
por: Aimulajiang, Kalibixiati, et al.
Publicado: (2019)

An informatic workflow for the enhanced annotation of excretory/secretory proteins of Haemonchus contortus
por: Zheng, Yuanting, et al.
Publicado: (2023)

Development and Potential Application of Ras Domain Containing Protein from Haemonchus contortus for Diagnosis of Goat Infection
por: Aimulajiang, Kalibixiati, et al.
Publicado: (2020)

Cloning and characterization of a selenium-independent glutathione peroxidase (HC29) from adult Haemonchus contortus
por: Sun, Wei, et al.
Publicado: (2012)

Recombinant elongation factor 1 alpha of Haemonchus contortus affects the functions of goat PBMCs
por: Ehsan, Muhammad, et al.
Publicado: (2020)

Characterization of a novel aspartyl protease inhibitor from Haemonchus contortus
por: Li, Baojie, et al.
Publicado: (2017)

Haemonchus contortus excretory and secretory proteins (HcESPs) suppress functions of goat PBMCs in vitro
por: Gadahi, Javaid Ali, et al.
Publicado: (2016)

Unveiling the Immunomodulatory Characteristics of Haemonchus contortus Ephrin Domain Containing Protein in the Parasite–Host Interactions
por: Aimulajiang, Kalibixiati, et al.
Publicado: (2020)

Hepatocellular carcinoma-associated antigen 59 of Haemonchus contortus modulates the functions of PBMCs and the differentiation and maturation of monocyte-derived dendritic cells of goats in vitro
por: Wang, QiangQiang, et al.
Publicado: (2019)

Immunoprotection in sheep against Haemonchus contortus using its thiol-purified excretory/secretory proteins
por: Arunkumar, Selvarayar
Publicado: (2012)

Advances in the Development of Anti-Haemonchus contortus Vaccines: Challenges, Opportunities, and Perspectives
por: Ehsan, Muhammad, et al.
Publicado: (2020)

Arginine kinase from Haemonchus contortus decreased the proliferation and increased the apoptosis of goat PBMCs in vitro
por: Ehsan, Muhammad, et al.
Publicado: (2017)

Characterization of a secreted macrophage migration inhibitory factor homologue of the parasitic nematode Haemonchus Contortus acting at the parasite-host cell interface
por: Wang, Yujian, et al.
Publicado: (2017)

Immunization of Goats with Recombinant Protein 14-3-3 Isoform 2(rHcftt-2) Induced Moderate Protection against Haemonchus contortus Challenge
por: Bu, Yongqian, et al.
Publicado: (2020)

Modulation of goat monocyte function by HCcyst-2, a secreted cystatin from Haemonchus contortus
por: Wang, Yujian, et al.
Publicado: (2017)

The N- and C-terminal carbohydrate recognition domains of Haemonchus contortus galectin bind to distinct receptors of goat PBMC and contribute differently to its immunomodulatory functions in host-parasite interactions
por: Lu, MingMin, et al.
Publicado: (2017)

Characterization of HC58cDNA, a putative cysteine protease from the parasite Haemonchus contortus
por: Muleke, Charles I., et al.
Publicado: (2006)

Transmembrane protein 147 (TMEM147): another partner protein of Haemonchus contortus galectin on the goat peripheral blood mononuclear cells (PBMC)
por: Li, Yan, et al.
Publicado: (2016)

Identification of a novel methyltransferase-type 12 protein from Haemonchus contortus and its effects on functions of goat PBMCs
por: Ehsan, Muhammad, et al.
Publicado: (2020)

Histidine acid phosphatase domain-containing protein from Haemonchus contortus is a stimulatory antigen for the Th1 immune response of goat PBMCs
por: Wen, Zhaohai, et al.
Publicado: (2022)

The GT1-TPS Structural Domain Protein From Haemonchus contortus Could Be Suppressive Antigen of Goat PBMCs
por: Wen, Zhaohai, et al.
Publicado: (2022)

Galectin Hco-gal-m from Haemonchus contortus modulates goat monocytes and T cell function in different patterns
por: Wang, Wang, et al.
Publicado: (2014)

Haemonchus contortus HcL6 promoted the Th9 immune response in goat PBMCs by activating the STAT6/PU.1/NF-κB pathway
por: Liang, Meng, et al.
Publicado: (2023)

Characterization of a rhodanese homologue from Haemonchus contortus and its immune-modulatory effects on goat immune cells in vitro
por: Wang, Yujian, et al.
Publicado: (2020)

Characterization of a secreted cystatin of the parasitic nematode Haemonchus contortus and its immune-modulatory effect on goat monocytes
por: Wang, Yujian, et al.
Publicado: (2017)

Transmembrane protein 63A is a partner protein of Haemonchus contortus galectin in the regulation of goat peripheral blood mononuclear cells
por: Yuan, Cheng, et al.
Publicado: (2015)

The Serine/Threonine-Protein Phosphatase 1 From Haemonchus contortus Is Actively Involved in Suppressive Regulatory Roles on Immune Functions of Goat Peripheral Blood Mononuclear Cells
por: Ehsan, Muhammad, et al.
Publicado: (2018)

Recombinant protein of Haemonchus contortus small GTPase ADP-ribosylation factor 1 (HcARF1) modulate the cell mediated immune response in vitro
por: Gadahi, Javaid Ali, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_e894bno0kfv080tuuieh2p2665