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Biological effects of selective COX-2 inhibitor NS398 on human glioblastoma cell lines

BACKGROUND: Cyclooxygenase-2 (COX-2), an inflammation-associated enzyme, has been implicated in tumorigenesis and progression of glioblastoma (GBM). The poor survival of GBM was mainly associated with the presence of glioma stem cells (GSC) and the markedly inflammatory microenvironment. To further...

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Detalles Bibliográficos
Autores principales:	Palumbo, Paola, Lombardi, Francesca, Augello, Francesca Rosaria, Giusti, Ilaria, Dolo, Vincenza, Leocata, Pietro, Cifone, Maria Grazia, Cinque, Benedetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222447/ https://www.ncbi.nlm.nih.gov/pubmed/32435158 http://dx.doi.org/10.1186/s12935-020-01250-7

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