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Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upregulating MMPs in Mesangial Cells

Transplantation of umbilical cord mesenchymal stem cells (UC-MSCs) is currently considered a novel therapeutic strategy for diabetic nephropathy (DN). However, the mechanisms by which UC-MSCs ameliorate renal fibrosis in DN are not well understood. Herein, we firstly investigated the therapeutic eff...

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Detalles Bibliográficos
Autores principales: Li, Hongde, Rong, Pengfei, Ma, Xiaoqian, Nie, Wei, Chen, Yan, Zhang, Juan, Dong, Qiong, Yang, Min, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222483/
https://www.ncbi.nlm.nih.gov/pubmed/32455132
http://dx.doi.org/10.1155/2020/3847171