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Novel vaccine technologies for the 21st century

Novel approaches to vaccine development include structure-based immunogen design, gene-based vaccine platforms and formulation of recombinant antigens with potent adjuvants. These technologies are producing encouraging results in the development of vaccines for globally important diseases such as tu...

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Detalles Bibliográficos
Autores principales: Mascola, John R., Fauci, Anthony S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222935/
https://www.ncbi.nlm.nih.gov/pubmed/31712767
http://dx.doi.org/10.1038/s41577-019-0243-3
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author Mascola, John R.
Fauci, Anthony S.
author_facet Mascola, John R.
Fauci, Anthony S.
author_sort Mascola, John R.
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description Novel approaches to vaccine development include structure-based immunogen design, gene-based vaccine platforms and formulation of recombinant antigens with potent adjuvants. These technologies are producing encouraging results in the development of vaccines for globally important diseases such as tuberculosis, influenza and respiratory syncytial virus. Here we highlight the most important developments in these areas over the past 18 months.
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spelling pubmed-72229352020-05-15 Novel vaccine technologies for the 21st century Mascola, John R. Fauci, Anthony S. Nat Rev Immunol Year in Review Novel approaches to vaccine development include structure-based immunogen design, gene-based vaccine platforms and formulation of recombinant antigens with potent adjuvants. These technologies are producing encouraging results in the development of vaccines for globally important diseases such as tuberculosis, influenza and respiratory syncytial virus. Here we highlight the most important developments in these areas over the past 18 months. Nature Publishing Group UK 2019-11-11 2020 /pmc/articles/PMC7222935/ /pubmed/31712767 http://dx.doi.org/10.1038/s41577-019-0243-3 Text en © This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Year in Review
Mascola, John R.
Fauci, Anthony S.
Novel vaccine technologies for the 21st century
title Novel vaccine technologies for the 21st century
title_full Novel vaccine technologies for the 21st century
title_fullStr Novel vaccine technologies for the 21st century
title_full_unstemmed Novel vaccine technologies for the 21st century
title_short Novel vaccine technologies for the 21st century
title_sort novel vaccine technologies for the 21st century
topic Year in Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222935/
https://www.ncbi.nlm.nih.gov/pubmed/31712767
http://dx.doi.org/10.1038/s41577-019-0243-3
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