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Comparable Effect of Two-Step Versus Extended Infusions on the Pharmacokinetics of Imipenem in Patients with Sepsis and Septic Shock

INTRODUCTION: The present study aimed to compare the pharmacokinetic/pharmacodynamic (PK/PD) parameters of imipenem administered by two-step (50% delivered in a 30-min bolus, 50% for the following 90 min) or extended (administered continuously for 2 h) infusion. METHODS: Patients with sepsis and sep...

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Detalles Bibliográficos
Autores principales:	Huang, Yingzi, Xu, Kang, Zhan, Ying, Zha, Xian, Liu, Songqiao, Xie, Jianfeng, Liu, Lin, Li, Qing, Shao, Hua, Yang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223128/ https://www.ncbi.nlm.nih.gov/pubmed/32277344 http://dx.doi.org/10.1007/s12325-020-01339-5

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