Development and bioanalytical method validation of an LC-MS/MS assay for simultaneous quantitation of 2-alkyl-4(1H)-quinolones for application in bacterial cell culture and lung tissue

Pseudomonas aeruginosa is an opportunistic pathogen that produces numerous exoproducts during infection that help it evade the host immune system and procure nutrients from the host environment. Among these products are a family of secreted 2-alkyl-4(1H)-quinolone metabolites (AQs), which exhibit a...

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Detalles Bibliográficos
Autores principales: Brewer, Luke K., Jones, Jace W., Blackwood, Catherine B., Barbier, Mariette, Oglesby-Sherrouse, Amanda, Kane, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223165/
https://www.ncbi.nlm.nih.gov/pubmed/31993728
http://dx.doi.org/10.1007/s00216-019-02374-0

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