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Design, synthesis, and screening of sulfonylurea-derived NLRP3 inflammasome inhibitors
Inflammasomes are multiprotein assemblies that produce robust inflammatory responses upon stimulation with pathogen- and/or danger-associated molecular patterns. Uncontrolled inflammasome activation has been linked to the pathophysiology of a wide array of disorders including life-threatening pathog...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223447/ https://www.ncbi.nlm.nih.gov/pubmed/32435125 http://dx.doi.org/10.1007/s00044-019-02466-7 |