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Heart Retransplantation: Candidacy, Outcomes, and Management

PURPOSE OF REVIEW: To describe the incidence and epidemiology of heart retransplantation in adults and children and to review the risk factors associated with adverse outcome following retransplantation to help guide recipient selection. RECENT FINDINGS: Heart retransplantation is associated with in...

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Detalles Bibliográficos
Autores principales: Barghash, Maya H., Pinney, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223608/
https://www.ncbi.nlm.nih.gov/pubmed/32435573
http://dx.doi.org/10.1007/s40472-019-00257-y
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author Barghash, Maya H.
Pinney, Sean P.
author_facet Barghash, Maya H.
Pinney, Sean P.
author_sort Barghash, Maya H.
collection PubMed
description PURPOSE OF REVIEW: To describe the incidence and epidemiology of heart retransplantation in adults and children and to review the risk factors associated with adverse outcome following retransplantation to help guide recipient selection. RECENT FINDINGS: Heart retransplantation is associated with inferior short-term and long-term survival when compared with primary heart transplantation and its use remains controversial although less so in the pediatric heart transplant population. SUMMARY: In the most recent era of heart transplantation, patients retransplanted for CAV, greater than 1 year from their primary transplant, and who are not in critical condition have improved survival compared with other retransplant recipients. Survival with retransplantation can approach that of primary transplantation when patients are appropriately selected. More research is needed regarding the optimal timing for retransplantation and the optimal management for patients after retransplantation.
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spelling pubmed-72236082020-05-15 Heart Retransplantation: Candidacy, Outcomes, and Management Barghash, Maya H. Pinney, Sean P. Curr Transplant Rep Thoracic Transplantation (J Kobashigawa and J Patel, Section Editors) PURPOSE OF REVIEW: To describe the incidence and epidemiology of heart retransplantation in adults and children and to review the risk factors associated with adverse outcome following retransplantation to help guide recipient selection. RECENT FINDINGS: Heart retransplantation is associated with inferior short-term and long-term survival when compared with primary heart transplantation and its use remains controversial although less so in the pediatric heart transplant population. SUMMARY: In the most recent era of heart transplantation, patients retransplanted for CAV, greater than 1 year from their primary transplant, and who are not in critical condition have improved survival compared with other retransplant recipients. Survival with retransplantation can approach that of primary transplantation when patients are appropriately selected. More research is needed regarding the optimal timing for retransplantation and the optimal management for patients after retransplantation. Springer International Publishing 2019-12-17 2020 /pmc/articles/PMC7223608/ /pubmed/32435573 http://dx.doi.org/10.1007/s40472-019-00257-y Text en © Springer Nature Switzerland AG 2019 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Thoracic Transplantation (J Kobashigawa and J Patel, Section Editors)
Barghash, Maya H.
Pinney, Sean P.
Heart Retransplantation: Candidacy, Outcomes, and Management
title Heart Retransplantation: Candidacy, Outcomes, and Management
title_full Heart Retransplantation: Candidacy, Outcomes, and Management
title_fullStr Heart Retransplantation: Candidacy, Outcomes, and Management
title_full_unstemmed Heart Retransplantation: Candidacy, Outcomes, and Management
title_short Heart Retransplantation: Candidacy, Outcomes, and Management
title_sort heart retransplantation: candidacy, outcomes, and management
topic Thoracic Transplantation (J Kobashigawa and J Patel, Section Editors)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223608/
https://www.ncbi.nlm.nih.gov/pubmed/32435573
http://dx.doi.org/10.1007/s40472-019-00257-y
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