The CTA1-DD adjuvant strongly potentiates follicular dendritic cell function and germinal center formation, which results in improved neonatal immunization

Vaccination of neonates and young infants is hampered by the relative immaturity of their immune systems and the lack of safe and efficacious vaccine adjuvants. Immaturity of the follicular dendritic cells (FDCs), in particular, appears to play a critical role for the inability to stimulate immune r...

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Detalles Bibliográficos
Autores principales: Schussek, Sophie, Bernasconi, Valentina, Mattsson, Johan, Wenzel, Ulf Alexander, Strömberg, Anneli, Gribonika, Inta, Schön, Karin, Lycke, Nils Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223721/
https://www.ncbi.nlm.nih.gov/pubmed/31959882
http://dx.doi.org/10.1038/s41385-020-0253-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223721/
https://www.ncbi.nlm.nih.gov/pubmed/31959882
http://dx.doi.org/10.1038/s41385-020-0253-2

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