The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections

The possibility of characterizing fluorescent immunoglobulins using spectrophotometric analysis as a testing method is considered. The comparative analysis of optical properties of fluorescent immunoglobulin preparations and their components—immunoglobulins and fluorochrome—is carried out. The obtai...

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Autores principales: Spitsyn, A. N., Utkin, D. V., Kireev, M. N., Ovchinnikova, M. V., Kuznetsov, O. S., Erokhin, P. S., Kochubei, V. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2020
Materias:
Applied Optics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224094/
https://www.ncbi.nlm.nih.gov/pubmed/32435071
http://dx.doi.org/10.1134/S0030400X20030182
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author Spitsyn, A. N.
Utkin, D. V.
Kireev, M. N.
Ovchinnikova, M. V.
Kuznetsov, O. S.
Erokhin, P. S.
Kochubei, V. I.
author_facet Spitsyn, A. N.
Utkin, D. V.
Kireev, M. N.
Ovchinnikova, M. V.
Kuznetsov, O. S.
Erokhin, P. S.
Kochubei, V. I.
author_sort Spitsyn, A. N.
collection PubMed
description The possibility of characterizing fluorescent immunoglobulins using spectrophotometric analysis as a testing method is considered. The comparative analysis of optical properties of fluorescent immunoglobulin preparations and their components—immunoglobulins and fluorochrome—is carried out. The obtained results testify that the proposed methodological approach of optical detection of labeled immunoglobulin molecules can be promising for tests on obtaining conjugates used in immunological tests on revealing specific antigens of causative agents of especially dangerous infections.
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spelling pubmed-72240942020-05-15 The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections Spitsyn, A. N. Utkin, D. V. Kireev, M. N. Ovchinnikova, M. V. Kuznetsov, O. S. Erokhin, P. S. Kochubei, V. I. Opt Spectrosc Applied Optics The possibility of characterizing fluorescent immunoglobulins using spectrophotometric analysis as a testing method is considered. The comparative analysis of optical properties of fluorescent immunoglobulin preparations and their components—immunoglobulins and fluorochrome—is carried out. The obtained results testify that the proposed methodological approach of optical detection of labeled immunoglobulin molecules can be promising for tests on obtaining conjugates used in immunological tests on revealing specific antigens of causative agents of especially dangerous infections. Pleiades Publishing 2020-04-30 2020 /pmc/articles/PMC7224094/ /pubmed/32435071 http://dx.doi.org/10.1134/S0030400X20030182 Text en © Pleiades Publishing, Ltd. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Applied Optics
Spitsyn, A. N.
Utkin, D. V.
Kireev, M. N.
Ovchinnikova, M. V.
Kuznetsov, O. S.
Erokhin, P. S.
Kochubei, V. I.
The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections
title The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections
title_full The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections
title_fullStr The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections
title_full_unstemmed The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections
title_short The Spectrophotometric Characteristic of Immunoglobulin Conjugates for Diagnostics of Causative Agents of Especially Dangerous Infections
title_sort spectrophotometric characteristic of immunoglobulin conjugates for diagnostics of causative agents of especially dangerous infections
topic Applied Optics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224094/
https://www.ncbi.nlm.nih.gov/pubmed/32435071
http://dx.doi.org/10.1134/S0030400X20030182
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