MiR-35 buffers apoptosis thresholds in the C. elegans germline by antagonizing both MAPK and core apoptosis pathways

Apoptosis is a genetically programmed cell death process with profound roles in development and disease. MicroRNAs modulate the expression of many proteins and are often deregulated in human diseases, such as cancer. C. elegans germ cells undergo apoptosis in response to genotoxic stress by the comb...

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Detalles Bibliográficos
Autores principales: Tran, Anh T., Chapman, Eric M., Flamand, Mathieu N., Yu, Bin, Krempel, Samuel J., Duchaine, Thomas F., Eroglu, Matthew, Derry, W. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224216/
https://www.ncbi.nlm.nih.gov/pubmed/30952991
http://dx.doi.org/10.1038/s41418-019-0325-6

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