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Luteolin attenuates doxorubicin-induced cardiotoxicity by modulating the PHLPP1/AKT/Bcl-2 signalling pathway

BACKGROUND: Luteolin (LUT) is a flavonoid found in vegetables and fruits that has diverse functions. Doxorubicin (DOX) is an anthracycline antibiotic that is frequently used for the treatment of various cancers. Unfortunately, the clinical efficacy of DOX is limited by its dose-related cardiotoxicit...

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Detalles Bibliográficos
Autores principales:	Zhang, YanDong, Ma, ChengYuan, Liu, ChunShui, Wei, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2020
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224230/ https://www.ncbi.nlm.nih.gov/pubmed/32435528 http://dx.doi.org/10.7717/peerj.8845

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