Chronic Sympathetic Hyperactivity Triggers Electrophysiological Remodeling and Disrupts Excitation-Contraction Coupling in Heart

The sympathetic nervous system is essential for maintenance of cardiac function via activation of post-junctional adrenergic receptors. Prolonged adrenergic receptor activation, however, has deleterious long-term effects leading to hypertrophy and the development of heart failure. Here we investigat...

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Detalles Bibliográficos
Autores principales: Joca, Humberto C., Santos‐Miranda, Artur, Joviano-Santos, Julliane V., Maia-Joca, Rebeca P. M., Brum, Patricia C., Williams, George S. B., Cruz, Jader S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224293/
https://www.ncbi.nlm.nih.gov/pubmed/32409748
http://dx.doi.org/10.1038/s41598-020-64949-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224293/
https://www.ncbi.nlm.nih.gov/pubmed/32409748
http://dx.doi.org/10.1038/s41598-020-64949-7

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