Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver

Liver injury triggers adaptive remodeling of the hepatic transcriptome for repair/regeneration. We demonstrate that this involves particularly profound transcriptomic alterations where acute induction of genes involved in handling of endoplasmic reticulum stress (ERS) is accompanied by partial hepat...

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Detalles Bibliográficos
Autores principales: Dubois, Vanessa, Gheeraert, Céline, Vankrunkelsven, Wouter, Dubois‐Chevalier, Julie, Dehondt, Hélène, Bobowski‐Gerard, Marie, Vinod, Manjula, Zummo, Francesco Paolo, Güiza, Fabian, Ploton, Maheul, Dorchies, Emilie, Pineau, Laurent, Boulinguiez, Alexis, Vallez, Emmanuelle, Woitrain, Eloise, Baugé, Eric, Lalloyer, Fanny, Duhem, Christian, Rabhi, Nabil, van Kesteren, Ronald E, Chiang, Cheng‐Ming, Lancel, Steve, Duez, Hélène, Annicotte, Jean‐Sébastien, Paumelle, Réjane, Vanhorebeek, Ilse, Van den Berghe, Greet, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224309/
https://www.ncbi.nlm.nih.gov/pubmed/32407006
http://dx.doi.org/10.15252/msb.20199156

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