Massively parallel interrogation and mining of natively paired human TCRαβ repertoires

T cells engineered to express antigen-specific T cell receptors (TCRs) are potent therapies for viral infections and cancer. However, efficient identification of clinical candidate TCRs is complicated by the size and complexity of T cell repertoires and the challenges of working with primary T cells...

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Detalles Bibliográficos
Autores principales: Spindler, Matthew J., Nelson, Ayla L., Wagner, Ellen K., Oppermans, Natasha, Bridgeman, John S., Heather, James M., Adler, Adam S., Asensio, Michael A., Edgar, Robert C., Lim, Yoong Wearn, Meyer, Everett H., Hawkins, Robert E., Cobbold, Mark, Johnson, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224336/
https://www.ncbi.nlm.nih.gov/pubmed/32393905
http://dx.doi.org/10.1038/s41587-020-0438-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224336/
https://www.ncbi.nlm.nih.gov/pubmed/32393905
http://dx.doi.org/10.1038/s41587-020-0438-y

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