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Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study

Fibroblast Growth Factor (FGF) dependent signalling is frequently activated in cancer by a variety of different mechanisms. However, the downstream signal transduction pathways involved are poorly characterised. Here a quantitative differential phosphoproteomics approach, SILAC, is applied to identi...

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Detalles Bibliográficos
Autores principales:	Cunningham, Debbie L., Sarhan, Adil R., Creese, Andrew J., Larkins, Katherine P. B., Zhao, Hongyan, Ferguson, Harriet R., Brookes, Katie, Marusiak, Anna A., Cooper, Helen J., Heath, John K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224374/ https://www.ncbi.nlm.nih.gov/pubmed/32409632 http://dx.doi.org/10.1038/s41598-020-64534-y

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